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R12007 3 the geometric mean targets may not be exceeded at any time. Tuberous sclerosis this is an autosomal dominant condition, due to mutations in either tsc1 on chromosome 9q hamartin or tsc2 on chromosome 16p tuberin with a prevalence of 115,000. The purpose of this study is to get a rough feel of the extent of the problem see sec. Introduction it appears that the number of metathesaurus terms with large degree of explicit ambiguity is increasing.
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